HML MIRING Validation

MIRING/HML Validation

http://miring.b12x.org/

• MIRING is a set of guiding principles that describe the Minimum Information for Reporting Immunogenomic NGS Genotyping

• HML 1.0 is a technical specification that allows information conforming to MIRING principles to be exchanged

  • But HML doesn’t have to be MIRING compliant
  • You can perfectly valid HML, yet doesn’t contain much information.
  • Here's an example of a perfectly valid HML 1.0.1 document, yet doesn't contain any useful information. It will pass XML Schema validation for HML, but is not MIRING compliant.

    <?xml version="1.0" ?>
    <hml xmlns="http://schemas.nmdp.org/spec/hml/1.0.1"
    version="1.0.1" >
    <sample id="1">
        <typing gene-family="HLA" date="2016-07-01">
            <typing-method/>
        </typing>
    </sample>
    </hml>

• We have developed a MIRING/HML validation service. A web interface is found here:

  • miring.b12x.org

• The MIRING HML Validator is available as a REST service, available to the public, hosted at

  • http://miring.b12x.org/validator/ValidateMiring/

• You can use this service programmatically using a POST request, with a single form parameter, "xml", containing the HML text.

  • Try this example using cURL:<br/ >

    $ curl -X POST --data-urlencode 'xml[]=<hml>...</hml>' http://miring.b12x.org/validator/ValidateMiring/
    

• Validator source is on github

  • https://github.com/nmdp-bioinformatics/MiringValidator

• More information including how to read a validation result and a description of current validation rules can be found here:

  • miring.b12x.org/MoreInfo.html

• a PDF of a presentation describing the MIRING validator can be found here:

  • https://github.com/nmdp-bioinformatics/dash/tree/master/miring_validator